Standard KAATSU protocols calls for the athlete to do 3-4 sets of each exercise. There should be between 15-20 seconds of rest between each set. If the appropriate Base SKU and Optimal SKU is set, the athlete will reach failure at a decreasing number of repetitions on each subsequent set (e.g., 25 reps on the first set, 15 reps on the second set, 5-10 reps on the third set).
Failure to move the limbs – either muscular or technical – is important in order to send a failure signal through the central nervous system to the brain. This will elicit a cascade of positive physiological reactions in the body.